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KMID : 1033120210100010001
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대한비만대사외과학회지
2021 Volume.10 No. 1 p.1 ~ p.8
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Obesity and Coronavirus Disease 2019
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Kim Min-Ji
Jeon Jae-Han
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Abstract
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Obesity, which is one of the most important noncommunicable diseases, has become an epidemic. With the outbreak of the coronavirus disease 2019 (COVID-19) pandemic, the collision of these two health risks has increased the threat of adverse events and serious threats to public health. In this review, the impact of obesity on COVID-19 severity and mortality is presented. The mechanism by which obesity increases susceptibility and severity is discussed. As a low-grade inflammatory disease, obesity provides a pro-inflammatory milieu by which adipose tissue expressing angiotensin converting enzyme 2, which is known as a receptor for severe acute respiratory syndrome coronavirus 2, works as a viral reservoir. Finally, the role of metabolic and bariatric surgeries during the COVID-19 era will be discussed.
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KEYWORD
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Coronavirus disease 2019, Obesity, Bariatric surgery, Angiotensin converting enzyme 2
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